The NIEHS Superfund Research Program (SRP) is hosting a Risk e-Learning webinar series emphasizing new approaches to elucidate mechanisms responsible for bioremediation. The series will feature innovative molecular, biochemical, cellular, and/or engineering tools to advance our understanding of the structural and functional properties of microorganisms or plants involved in the bioremediation of hazardous substances. The first session will serve as an introduction to the series and will touch on opportunities to build linkages with other microbiome fields of study, such as the human microbiome. SRP Director William A. Suk, Ph.D., will introduce the series, highlighting SRP grantees' contribution to innovation in bioremediation. The SRP funds multidisciplinary research to address the complex and evolving challenges associated with Superfund and related hazardous waste sites, including the development of new remediation technologies. Dr. Suk will provide an overview of the findings from past SRP bioremediation research, from basic discoveries to cost-saving field applications, and will introduce potential opportunities to expand the bioremediation toolbox. James Tiedje, Ph.D., from the Michigan State University SRP Center, will discuss the past and future of microbiome science, which transcends habitats. The major questions, methods, and underlying biology of microbiome science are very similar, so much is transferable among studies in the soil, gut, ocean, and other systems. There are important differences in the details, but the details are not the starting point. In this talk, Tiedje will summarize what we have learned from the past in microbial ecology that helps us project the future and then will speculate on that future and how it may impact and likely facilitate SRP-relevant microbiome research. Microbial communities mediate important transformations of environmental arsenic. These biotransformations dictate the bioavailability and toxicity of arsenic in environments ranging from soil to the human gut. Raina Maier, Ph.D., and Paul Carini, Ph.D., from the University of Arizona SRP Center, will discuss new integrative tools that combine plant transcriptomics, microbial meta(genomics), and high throughput microbial culturing to link key taxa to specific arsenic biotransformations important to both phytoremediation processes and human health. To view this archive online or download the slides associated with this seminar, please visit http://www.clu-in.org/conf/tio/SRPBio1_093019/