Contaminated Site Clean-Up Information (CLU-IN): Internet Seminar Audio Archives

Since 1998, The Contaminated Site Clean-Up Information (CLU-IN) website has presented Internet Seminars covering a wide variety of technical topics related to hazardous waste characterization, monitoring, and remediation. For each seminar topic, we have selected the highest-quality offering for placement in our archives. Beginning in May 2005, we began offering these archives via podcast, and this feed contains all seminars archived in the last 6 months. For a complete list of seminars archived since 2000 and videos of selected seminars archived since 2012, please visit http://clu-in.org/live/archive/. Our Rehabilitation Act Notice for reasonable accommodation is available at http://clu-in.org/training/accommodation.cfm. CLU-IN was developed by the U.S. Environmental Protection Agency (EPA) but is intended as a forum for all waste remediation stakeholders. For more information and to view upcoming live offerings, please visit http://clu-in.org/live/. For a complete list of RSS feeds available on CLU-IN, please visit http://clu-in.org/rss/about/.

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Slides for "Bioavailability of Contaminants in Soil: Considerations for Human Health Risk Assessment," Jan 23, 2020


Risk-based cleanup goals are often calculated assuming that chemicals present in soil are absorbed by humans as efficiently as the chemicals dosed during the toxicity tests used to determine regulatory toxicity values (such as the Reference Dose or Cancer Slope Factor). This assumption can result in inaccurate exposure estimates and associated risks for some contaminated sites because the amount of a chemical absorbed (the chemical's bioavailability) from contaminated soil can be a fraction of the total amount present. Properly accounting for soil-chemical interactions on the bioavailability of chemicals from soil can lead to more accurate estimates of exposures to soil contaminants and improve risk assessments by decreasing uncertainty. The basis for this training course is the ITRC guidance: Bioavailability of Contaminants in Soil: Considerations for Human Health Risk Assessment (BCS-1). This guidance describes the general concepts of the bioavailability of contaminants in soil, reviews the state of the science, and discusses how to incorporate bioavailability into the human health risk assessment process. This guidance addresses lead, arsenic, and polycyclic aromatic hydrocarbons (PAHs) because evaluating bioavailability is better understood for these chemicals than for others, particularly for the incidental ingestion of soil. The target audience for this guidance and training course are: Project managers interested in decreasing uncertainty in the risk assessment which may lead to reduced remedial action costs. Risk assessors new to bioavailability or those who want additional confidence and training in the current methods and common practices for using bioavailability assessment to more accurately determine human health risk at a contaminated site.As a participant in this training you should learn to:Value the ITRC document as a "go-to" resource for soil bioavailability Apply the decision process to determine when a site-specific bioavailability assessment may be appropriate Use the ITRC Review Checklist to develop or review a risk assessment that includes soil bioavailability Consider factors that affect arsenic, lead and PAH bioavailability Select appropriate methods to evaluate soil bioavailability Use tools to develop site-specific soil bioavailability estimates and incorporate them into human health risk assessmentLearners can envision themselves implementing the ITRC guidance through case study applications. Training participants are encouraged to view the associated ITRC guidance, Bioavailability of Contaminants in Soil: Considerations for Human Health Risk Assessment (BCS-1) prior to attending the class.


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 2020-01-24  n/a