This Week in Virology

TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.


episode 670: Coronavirus vaccine preparedness with Kizzmekia Corbett

Kizzmekia Corbett joins TWiV to review her career and her work on respiratory syncytial virus, influenza virus, and coronaviruses and coronavirus vaccines, including her role in development and testing of a spike-encoding mRNA vaccine, and then we review the Nobel Prize for discovery of hepatitis C virus.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler and Brianne Barker

Guest: Kizzmekia Corbett

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Links for this episode

  • Pre-fusion structure of CoV spike (Nature)
  • Pre-fusion structure of SARS-CoV-2 spike (Science)
  • Evaluation of mRNA-1273 in nonhuman primates (NEJM)
  • SARS-CoV-2 vaccine from pandemic preparedness (Nature)
  • Nanoparticulate universal influenza vaccine from stem antigens (mBio)
  • Biological safety officer position at Columbia U
  • Medicine Nobel Prize for Hepatitis C virus (pdf)
  • Alter's work on non-A non-B hepatitis (paper one, paper two)
  • Houghton: single clone of HCV genome (Science)
  • Rice: Transmission of hepatitis C to chimpanzee (Science)
  • Charlie Rice on TWiV 392
  • Chemistry Nobel Prize to Doudna and Charpentier (
  • FDA releases stricter guidelines for COVID-19 vaccines (NY Times, FDA pdf)
  • Bullet points of Das coronavirus
  • Recovery of 1918 influenza virus stories (one, two)
  • Letters read on TWiV 670
  • Timestamps by Jolene. Thanks!

Weekly Science Picks

Brianne - COVID-19 in Molecular Detail for Teaching
Kathy – Mars shining brightest since 2003
Rich - Lost Prologue
Vincent - Girl from Ipanema is weirder than you thought

Listener Pick

Sandra - Learn Medical Research

Intro music is by Ronald Jenkees

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 2020-10-08  2h7m