This Week in Virology

TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.


episode 675: Forget what you've herd about immunity

Daniel Griffin provides a clinical report on COVID-19, then we discuss Bill Foege’s letter to CDC director Robert Redfield, the false promise of herd immunity for COVID-19, secret blueprints for SARS-CoV-2 vaccine trials released, and neuropilin-1 as a possible entry protein for the virus.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

Guest: Daniel Griffin

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Links for this episode
  • Excess COVID-19 Deaths by Age and Race and Ethnicity (MMWR)
  • Excess COVID-19 deaths (JAMA)
  • SARS-CoV-2 transmission (CDC)
  • UK challenge trial (Nature)
  • Inflammatory cytokine signature for severe COVID-19 (Nature)
  • Death in AstraZeneca vaccine trial (Reuters)
  • Herpetic Legion – Reactivation (YouTube)
  • Tech position with Dr. Rosenfeld
  • Biological safety officer position at CUMC
  • Support MicrobeTV at Parasites Without Borders
  • Foege letter to Redfield (text, NPR article)
  • False promise of herd immunity (Nature)
  • Secret vaccine plans released (NY Times)
  • Neuropilin-1 and SARS-CoV-2 entry (paper one, two)
  • Letters read on TWiV 675
  • Timestamps by Jolene. Thanks!
Weekly Science Picks

Dickson – Nikon Small World Photography Competition
Brianne – Modeling Herd Immunity for measles
Alan – Small Gods by Terry Pratchett
Rich – Boundless Body Radio Bethany and Casey Ruff
Vincent – The Twenty-One Balloons by William Pene du Bois

Intro music is by Ronald Jenkees

Send your virology questions and comments to


 2020-10-25  2h54m