the bioinformatics chat

A podcast about computational biology, bioinformatics, and next generation sequencing.

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episode 52: How 23andMe finds identical-by-descent segments with William Freyman


In this episode, Will Freyman talks about identity-by-descent (IBD): how it’s used at 23andMe, and how the templated positional Burrows-Wheeler transform can find IBD segments in the presence of genotyping and phasing errors.

Links:

  • Fast and robust identity-by-descent inference with the templated positional Burrows-Wheeler transform (William A. Freyman, Kimberly F. McManus, Suyash S. Shringarpure, Ethan M. Jewett, Katarzyna Bryc, the 23andMe Research Team, Adam Auton)
  • 23andMe research


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 2020-10-27  42m