episode 734: Weiss hath no furin like a virus scorned
Susan Weiss returns to TWiV to discuss coronavirus entry into cells and the role of spike protein cleavage by proteases, why lab escaped hypotheses for SARS-CoV-2 are unlikely, and modulation of innate immune responses during infection.
Hosts: Vincent Racaniello, Rich Condit, Alan Dove, Brianne Barker, and Amy Rosenfeld
Guest: Susan Weiss
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Links for this episode- CoV pathogenesis in CNS (J Neuro Pharm)
- SARS-CoV-2 induces dsRNA-mediated innate responses (bioRxiv)
- Screen of FDA-approved drugs (J Viral)
- Letters read on TWiV 735
- Timestamps by Jolene. Thanks!
Brianne – Tiktok of How mRNA Vaccines Work
Alan – Dark
Rich – Unmixing Color Machine (Ultra Laminar Reversible Flow) – Smarter Every Day 217
Amy – MOMA Calder exhibit, reviewed in NYTimes
Vincent – Ripple Training (free YouTube channel)
Ruth – 100 million year old seafloor bacteria resuscitated
Iradis – Linda Zall, CIA spy for science
Intro music is by Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv