Hosted by Bill Curtis and quadruple board certified Dr. Steven Taback, Medicine, We’re Still Practicing sits down with doctors from the world’s most preeminent hospitals for insights into their research, practice, and education. The first in this dedicated series is Johns Hopkins Medicine, with the goal of not only to share the magnificent work being done by these hospitals and doctors, but for them to be able to use it as a high-quality educational tool and platform to share insights and research to a large, receptive audience. Medicine, We’re Still Practicing is a thoroughly informative and realistic podcast that speaks not only to the layman medical audience, but appeals to the medical community as well. No topic is off limits, from the insurance industry and universal healthcare to the latest medical advances and all of the quackery and snake oil salesmen you should avoid. However, in accordance with good bedside manner, Dr. Taback and his guests from the medical community keep the conversation light and informative. An important listen during these times of medical uncertainty and differed opinions.
https://www.curtco.com/stillpracticing
episode 30: 30 - Killing Cancer with Mice
On this episode, Bill and Dr. Steve are joined by three members of the Certis Oncology team: CEO Peter Ellman, Dr. Arun Singh M.D., and Surgical Oncologist Dr. Fritz Eilber M.D.
Certis is an early stage biotech company with a focus on advancing translational oncology through the O-PDX technique. O-PDX standing for “patient derived xenografts” are models of cancer where the tissue or cells from a patient's tumor are implanted into an immunodeficient or humanized mouse. Certis acquires intimate knowledge about the biology, chemistry and evolution of individual cancers to empower patients, inform treatment strategies and advance the next generation of oncology therapeutics. We think you’ll be just as inspired by this episode as we are.
Episode Timestamps:
3:40 Why is treating cancer still such a mystery?
4:30 What is cancer?
5:24 What is the Certis Oncology all about?
6:54 Petri Dish vs Mouse Model
7:39 The novelty of using immunosuppressive mice
9:35 How does Certis scale this model to the whole world
10:57 Can you start your oncology treatment with the mouse method via Certis?
12:08 Do insurance companies play ball with mouse model research?
13:15 What should general surgeons outside of Certis be doing with biopsy specimens?
14:32 What is the turnaround time on the mouse model research?
16:27 What is the dynamic with Certis and an individuals specific oncologist?
21:33 Peter Ellman shares how Certis got started
26:00 Does a tumor that is implanted in a mouse have the same likelihood of traveling to other organs as it would in a human?
28:22 Can patients request having work done with Certis?
30:13 Where is Certis getting it’s funding from, and what is the future dynamic with insurance companies?
33:00 Can the model work for other diseases outside cancer?
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Hosted by: Dr. Steven Taback & Bill Curtis
Produced and Edited by: AJ Moseley
Sound Engineering by: Steve Reickeberg
Theme Music by: Celleste and Eric Dick
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