This Week in Virology

TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.


episode 829: Antiviral and cytotoxically empowered for COVID-19

A TWiV duo reviews how SARS-CoV-2 attacks the olfactory mucosa but spares the olfactory bulb, vaccination with BNT162b2 induces virus-specific stem cell memory T cells, and development of an oral protease inhibitor for the treatment of COVID-19.

Hosts: Vincent Racaniello and Brianne Barker

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Links for this episode
  • How SARS-CoV-2 attacks olfactory mucosa (Cell)
  • SARS-CoV-2-specific stem cell memory T cells after mRNA vaccine (Sci Immunol)
  • Oral SARS-CoV-2 protease inhibitor (Science)
  • Paxlovid phase 2/3 trial preliminary results (Pfizer)
  • Letters read on TWiV 829
  • Timestamps by Jolene. Thanks!
Weekly Picks

Brianne – Coronavirus Neutralizing Antibodies and mRNA Vaccine Video
Vincent – MHC restriction of cytotoxic T cell lysis (Nobel description)

Listener Picks

Lisa – Shall Furnish Medicine
Bistra – Saving the World by Julia Alvarez

Intro music is by Ronald Jenkees

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 2021-11-14  1h43m