episode 829: Antiviral and cytotoxically empowered for COVID-19
A TWiV duo reviews how SARS-CoV-2 attacks the olfactory mucosa but spares the olfactory bulb, vaccination with BNT162b2 induces virus-specific stem cell memory T cells, and development of an oral protease inhibitor for the treatment of COVID-19.
Hosts: Vincent Racaniello and Brianne Barker
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Links for this episode- How SARS-CoV-2 attacks olfactory mucosa (Cell)
- SARS-CoV-2-specific stem cell memory T cells after mRNA vaccine (Sci Immunol)
- Oral SARS-CoV-2 protease inhibitor (Science)
- Paxlovid phase 2/3 trial preliminary results (Pfizer)
- Letters read on TWiV 829
- Timestamps by Jolene. Thanks!
Brianne – Coronavirus Neutralizing Antibodies and mRNA Vaccine Video
Vincent – MHC restriction of cytotoxic T cell lysis (Nobel description)
Lisa – Shall Furnish Medicine
Bistra – Saving the World by Julia Alvarez
Intro music is by Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv