episode 843: COVID-19 clinical update #93 with Dr. Daniel Griffin
In COVID-19 clinical update #93, Dr. Griffin summarizes Omicron fitness, S-gene target failure, monoclonal efficacy against Omicron, vaccination, monoclonals, and disease in children, persistence of memory B cells in the elderly, infection and vaccine induced immunity, protection against severe illness and death by a third mRNA vaccine dose, high flow oxygen versus intubation, and therapeutic anticoagulation.
Hosts: Daniel Griffin and Vincent Racaniello
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Links for this episode- Variant updates (CDC)
- List of diagnostic kits (Global Fund, pdf)
- B1.1.529 escapes most antibodies (bioRxiv)
- mRNA vaccine third dose and Omicron (medRxiv)
- Outpatient strategies children and adolescents (AAP)
- Memory B cells persist in elderly (J Clin Invest)
- mRNA booster effect against Delta (Clin Inf Dis)
- Azithromycin meta-analysis (J Antimicrob Chemo)
- High-flow oxygen vs intubation (JAMA)
- Therapeutic anticoagulation (Ann Int Med)
- Africa cases surge (CIDRAP)
- Letters read on TWiV 843
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv