This Week in Virology

TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.

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episode 949: Clinical update with Dr. Daniel Griffin


In his weekly clinical update Dr. Griffin discusses progress toward poliomyelitis eradication in Pakistan, polio by the numbers , influenza and COVID-19 vaccination coverage among health care personnel, phase 1/2a safety and immunogenicity of an adenovirus 26 vector RSV vaccine encoding prefusion F in adults 18–50 years and RSV seropositive children 12–24 months, receipt of first and second doses of JYNNEOS vaccine for prevention of Monkeypox, distinguishing SARS-CoV-2 persistence and reinfection, Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages, association between regular physical activity and the protective effect of vaccination against SARS-CoV-2 in a South African case, COVID-19 outcomes in solid organ transplant recipients who received Tixagevimab-cilgavimab Prophylaxis and/or Bebtelovimab treatment, Omicron sublineage BA.2.75.2 exhibits extensive escape from neutralizing antibodies, and Tocilizumab versus Baricitinib in hospitalized patients with severe COVID-19.

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Links for this episode
  • Progress toward Poliomyelitis eradication (CDC)
  • Polio by the numbers (JID)
  • Influenza & COVID-19 vaccination coverage among health care personnel (CDC)
  • Phase 1/2a Safety & Immunogenicity of an adenovirus RSV Vaccine (JID)
  • Receipt of first & second doses of JYNNEOS vaccine  (CDC)
  • Distinguishing SARS-CoV-2 persistence and reinfection (CID)
  • Remdesivir fact sheet for providers (Veklury)
  • Bebtelovimab fact sheet for providers (FDA)
  • Novavax triggers potent neutralization of Omicron sub-lineages (bioRxiV)
  • Association between physical activity & vaccination protective effect (BMJ)
  • PAXLOVID patient eligibility screening checklist (FDA)
  • COVID-19 outcomes in solid organ transplant recipients who received monoclonal antibodies (Transplantation)
  • Omicron BA.2.75.2 exhibits escape from neutralizing antibodies (bioRxiV)
  • Tocilizumab vs. Baricitinib in hospitalized patients with severe COVID-19 (CMI)
  • Dr. Griffin’s treatment guide (pdf)
  • Contribute to Floating Doctors fundraiser at PWB
  • Letters read on TWiV 949
  • Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv


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 October 29, 2022  45m