AJP-Heart and Circulatory Podcasts

Commentary and discussion focusing on featured articles from the American Journal of Physiology - Heart and Circulatory Physiology.




episode 87: Differential Control of Sympathetic Outflow in Young Humans

What drives variability in muscle sympathetic nerve activity among healthy individuals? Associate Editor Nisha Charkoudian (U.S. Army Research Institute of Environmental Medicine) explores this central question in a new interview with lead author Philip...



episode 86: Personalized Medicine in HFpEF

Why is biological phenotyping needed to improve current clinical treatment of heart failure with preserved ejection fraction (HFpEF)? Listen as Guest Editor Maria Bloksgaard (University of Southern Denmark) interviews lead author Vanessa van Empel (Maas...


 2018-12-05  13m

episode 85: Statistical Considerations in Reporting Cardiovascular Research

“As biomedical scientists, we have an obligation to get the numbers right,” declares AJP-Heart and Circulatory Physiology Editor-in-Chief Dr. Irving H. Zucker in the opening of this insightful discussion on, that’s right, statistics. This isn’t your run...


 2018-10-19  12m

episode 84: Unregulated Ca2+ Cycling Exacerbates DMD Cardiomyopathy

Does improving intracellular calcium handling through cardiac-specific phospholamban ablation in a mouse model of Duchenne Muscular Dystrophy affect the development of cardiomyopathy? In this podcast, Associate Editor Junichi Sadoshima (Rutgers New Jers...


 2018-10-16  11m

episode 83: Sex Differences in Depression-Like Behavior Post Myocardial Infarction

Nearly one-fifth of heart failure patients develop depression or depression-like symptoms and are therefore at greater risk for additional cardiac events and mortality. Inflammation in the hypothalamus has been shown to play a role in heart failure prog...


 2018-10-12  18m

episode 82: Piezo1 Mechanotransduction in the Uterine Circulation

Is the Piezo1 cation channel the sensor for shear stress that triggers uterine blood vessel growth and vasodilation in pregnancy? Listen as Editor in ...


 2018-09-14  15m

episode 81: Vascular Smooth Muscle Actin Depolymerization

Is actin depolymerization the mechanism that causes vasodilation in small resistance arterioles? Listen as Associate Editor Robert Hester (University of Mississippi Medical Center) and ...


 2018-09-02  12m

episode 80: Reversal of Microvascular Dysfunction

Can existing vascular disease be reversed? Listen as Associate Editor Robert Hester (University of Mississippi Medical Center) interviews lead author Jefferson Frisbee (University of ...


 2018-08-28  12m

episode 79: Fibroblast Phenotypic Changes in the Aging Heart

Why is it important to understand resident cardiac fibroblasts and how they change with aging? In this thought-provoking podcast, Deputy Editor Merry Lindsey (University ...


 2018-08-08  13m

episode 78: Japanese Language Podcast: Type of Resistance Exercise and Endothelial Function

In this special Japanese-language podcast, we explore an important exercise physiology question: Can high-intensity resistance exercise, combined with low repetitions, maintain endothelial function? Listen ...


 2018-07-18  9m