This Week in Virology

TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.

http://www.microbe.tv/twiv

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      episode 467: Jon and Ted's Excellent Adventure


      Jon and Teddy Yewdell join the TWiV team to talk about their careers, their research, and the problems with biomedical research.

      Hosts: Vincent Racaniello, Alan Dove,and Rich Condit

      Guest: Jon Yewdell and Teddy Yewdell

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      Links for this episode Jon Yewdell laboratory Chaudhuri laboratory Truth Wins by Jon Yewdell (epub or mobi download) Noncoding RNAs and class switch recombination (Int Imm) Translating DRiPs (J Leuk Biol) Lamprey VLRP respon...


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      1h39m
       

      The Capsid Club


      From Indiana University, Vincent and Kathy speak with Tuli Mukhopadhyay, John Patton, and Adam Zlotnick about their careers and their work on alphaviruses, hepatitis B virus, and rotaviruses.

      Host: Vincent Racaniello and Kathy Spindler

      Guests: Tuli Mukhopadhyay, John Patton, and Adam Zlotnick

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      Links for this episode Mukhopadhyay lab Patton lab Zlotnick lab Tuli on Twitter Palmitoylation of Sindbis virus TF protein (J Virol) Hepatitis B viru...


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      1h5m
       

      episode 465: Theodora the explorer


      Theodora Hatziioannou joins the TWiV team to discuss a macaque model for AIDS, and how a cell protein that blocks HIV-1 infection interacts with double-stranded RNA.

      Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

      Guest: Theodora Hatziioannou

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      Links for this episode ASU-UofA Joint Virology Symposium Laboratory of Retrovirology, Rockefeller University HIV-1-induced AIDS in monkeys (Science) APOBEC3H ...


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      1h50m
       

      episode 464: Boston baked viruses


      At Tufts University Dental School in Boston, Vincent speaks with Katya Heldwein and Sean Whelan about their careers and their work on herpesvirus structure and replication of vesicular stomatitis virus.

      Host: Vincent Racaniello

      Guests: Katya Heldwein and Sean Whelan

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      Links for this episode Crystal structure of HSV gB (Science) Crystal structure of HSV fusion regulator gH-gL (Nat Struct Mol Biol) Nuclear Exodus: Herpesviruses Lead the Way (...


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      1h27m
       

      episode 463: We haven't meth but these names ring Nobel


      The TWiViridae review the 2017 Nobel Prizes for cryoEM and circadian rhythms, and discuss modulation of plant virus replication by RNA methylation.

      Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

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      Links for this episode Truth Wins by Jonathan Yewdell (epub or mobi) Gabriel Victora awarded MacArthur Prize Forty Years of mRNA Splicing (CSH) 2017 Chemistry Nobel: Jacques Dubochet, Joachim Frank, Richard Hend...


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      1h44m
       2017-10-15

      Tear it up with David Tuller


      David Tuller returns to discuss his efforts to expose the methodological and ethical problems with the PACE trial for ME/CFS.

      Hosts: Vincent Racaniello

      Guest: David Tuller

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      Links for this episode All of David's ME/CFS articles at virology blog David Tuller on Twitter Through the Shadowlands by Julie Rehmeyer

      Intro music is by Ronald Jenkees.

      Send your virology questions and comments to twiv@microbe.tv


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      1h7m
       2017-10-14

      episode 462: TWiV 462: Splicing RNA with Phillip A. Sharp


      Vincent speaks with 1993 Nobel Laureate Phillip A. Sharp about his career and his seminal discovery of RNA splicing in mammalian cells, which changed our understanding of gene structure.

      Hosts: Vincent Racaniello

      Guest: Phillip A. Sharp

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      Links for this episode Meet the Microbiologist Sharp Laboratory Spliced segments of adenovirus late mRNA (PNAS) Video of this interview (YouTube)

      This episode is brought to you by the Defense Threat Red...


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      38m
       2017-10-07

      episode 461: Gotta trace them all!


      The TWiVers discuss the declining readability of scientific texts, and review the use of self-inactivating rabies virus for tracing neural circuits.

      Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler

      Guest: Brianne Barker

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      Links for this episode Meet the Microbiologist TWiV 1: West Nile Virus Decreasing readability of scientific texts (eLife) Measure text readability Tracing neural circuits with self...


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      2h7m
       2017-09-30

      episode 460: Penn, a great sandbox for science


      Vincent travels to the University of Pennsylvania and speaks with virologists Gary Cohen, Scott Hensley, Carolina Lopez, and Susan Weiss about their careers and their research.

      Host: Vincent Racaniello

      Guests: Gary Cohen, Scott Hensley, Carolina Lopez, and Susan Weiss

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      Links for this episode Cohen Laboratory Hensley Laboratory Lopez Laboratory Weiss Laboratory

      This episode is brought to you by the Defense Threat Reduction Agency. Part o...


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      1h32m
       2017-09-24

      episode 459: Polio turns over a new leaf


      The TWiV team reviews the first FDA approved gene therapy, accidental exposure to poliovirus type 2 in a manufacturing plant, and production of a candidate poliovirus vaccine in plants.

      Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

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      Links for this episode ASM Conference on Viral Manipulation of Nuclear Processes ASM Public Outreach Fellowship Kymriah approved (PennMed) CAR T cells (NCBI) Cost of Kymriah ...


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      1h44m
       2017-09-17