This Week in Virology

TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.

Eine durchschnittliche Folge dieses Podcasts dauert 1h36m. Bisher sind 773 Folge(n) erschienen. Dies ist ein wöchentlich erscheinender Podcast.

Gesamtlänge aller Episoden: 50 days 14 hours 5 minutes


episode 743: Shape-shifting viruses

The TWiVsters explain how the shape of pleomorphic virus particles – spherical or filamentous – determines the probability of virus attachment and fusion, and resistance to selective pressure such as antibodies that block cell entry.



episode 742: De-fusing COVID-19

TWiV reviews a drug screen for inhibitors of syncytium formation, the fusing of cells caused by SARS-CoV-2, which reveals that the process is regulated by a calcium-activated ion channel and scrambles that is inhibited by the anti-parasite drug...



episode 741: COVID-19 clinical update #57 with Dr. Daniel Griffin

In COVID-19 clinical update #57, Daniel Griffin covers children and MIS-C, school opening plans, transmission event with masks, fomite transmission, diagnostic test performance, AZ vaccine and blood clots, and long COVID and the effect of vaccines.



episode 740: Complementation will get you everywhere

The Guardians of the TWiV-o-verse discuss the process of codon deoptimization for the production of experimental infectious attenuated viral vaccines, and how a respiratory syncytial virus with 619 base changes was rescued by genomes with very large...


 2021-04-08  1h36m

episode 739: COVID-19 convalescent plasma with Arturo Casadevall

Arturo Casadevall joins TWiV to discuss the use of convalescent plasma to treat COVID-19, including a history of the process, how plasma is prepared and tested, why it is difficult to conduct randomized clinical trials, how this treatment has fared...


 2021-04-04  1h55m

episode 738: COVID-19 clinical update #56 with Dr. Daniel Griffin

In COVID-19 clinical update #56, Daniel Griffin note increasing hospitalization in children and young adults, Pfizer vaccine efficacy results in 12-15 year olds, rapid self administered nucleic acid and antigen tests, mRNA vaccine efficacy in real...


 2021-04-03  35m

episode 737: SARS-CoV-2 in NYC wastewater

John, Monica, and Davida join TWiV to discuss development of a method to detect SARS-CoV-2 in raw sewage from all 14 of New York City’s treatment plants, and its use to determine the presence of the genome throughout the pandemic and detection of...


 2021-04-01  1h55m

episode 736: Rhapsody in T with Alessandro Sette

Alessandro Sette joins TWiV to discuss the role of T cells in COVID-19, the finding that amino acid changes in SARS-CoV-2 variants of concern have a negligible impact on T cell reactivity in convalescent patients and vaccinees, and whether a next...


 2021-03-28  2h1m

episode 735: COVID-19 clinical update #735 with Dr. Daniel Griffin

In COVID-19 clinical update #55, Daniel Griffin reviews recommendations for keeping transmission low in school settings, optimal testing strategies for schools and businesses, impact of vaccines on asymptomatic infections, vaccine safety in PASC...


 2021-03-26  39m

episode 734: Weiss hath no furin like a virus scorned

Susan Weiss returns to TWiV to discuss coronavirus entry into cells and the role of spike protein cleavage by proteases, why lab escaped hypotheses for SARS-CoV-2 are unlikely, and modulation of innate immune responses during infection.


 2021-03-21  2h10m