Each episode of AJP Audio brings you an in-depth look at one of the articles featured in that month’s issue of The American Journal of Psychiatry, the official journal of the American Psychiatric Association. Wide-ranging interviews with article authors cover the background, rationale, main findings, and future implications of the research. This podcast is subject to the Terms of Use at ww.psychiatry.org. The views and opinions expressed in this podcast are those of the individual speakers only and do not necessarily represent the views of the American Psychiatric Association, its officers, trustees, or members. The content of this podcast is provided for general informational purposes only and is not intended as, and shall not be understood or construed as, medical or any other type of professional advice nor does it represent any statement of the standard of care. We strongly recommend that any listener follow the advice of physicians directly involved in their care and contact their local emergency response number for any medical emergency. The information within this podcast is provided as-is and is not guaranteed to be correct, complete, or accurate.
https://ajp.psychiatryonline.org/audio
March 2023: Adjunctive Cariprazine for the Treatment of Patients With Major Depressive Disorder
Dr. Gary S. Sachs (Harvard Medical School) joins us for the for the March episode of AJP Audio, discussing the results from a phase 3 study looking at the use of atypical antipsychotic cariprazine as an adjunctive treatment for major depression in conjunction with antidepressants. Afterwards, we’ll be joined once again by AJP Editor-in-Chief Dr. Ned Kalin to discuss the rest of the March issue.
Transcript
- Sachs interview [00:47]
- Why is treating major depressive disorder in patients proven to be such a challenge for clinicians? [01:54]
- Why cariprazine in conjunction with antidepressants? [02:37]
- Atypical antipsychotics and antidepressants [03:22]
- Atypical antipsychotics and side effects [05:23]
- Limitations [07:09]
- Clinical implications for the treatment of major depressive disorder [08:29]
- What’s next for your research? [09:15]
- Kalin interview [10:09]
- Sachs et al. [10:25]
- Hasseris et al. [12:35]
- Visontay et al. [15:15]
- Dunlop et al. [17:10]
- Elbau et al. [19:56]
Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Stitcher, Spotify, or wherever you listen to it.
Subscribe to the podcast here.
Listen to other podcasts produced by the American Psychiatric Association.
Browse articles online.
How authors may submit their work.
Follow the journals of APA Publishing on Twitter.
E-mail us at ajp@psych.org