This Progress in Research webinar series will showcase research from 11 new and renewed Multiproject Center grantees, funded by SRP in 2022. These awards were made as part of the P42 grant solicitation RFA-ES-20-014. In the four-part series, awardees will highlight their research projects, accomplishments, and next steps. The University of New Mexico SRP Center collaborates with Indigenous partners from Navajo Nation and Laguna Pueblo to reduce the health risks associated with exposure to metal mixtures from abandoned uranium mines. Center scientists use community informed, solution-oriented team science to prevent exposures and protect health through development of partnered environmental and clinical interventions. The Columbia University Northern Plains SRP Center studies hazardous metals in drinking water, which are common contaminants near Superfund sites and abandoned uranium mines that play a role in the high burden of heart disease and diabetes affecting Tribal communities in the U.S. Northern Plains. The center will continue to generate knowledge to understand the underlying mechanisms and possible solutions to exposures to hazardous metal mixtures using systems science, local community knowledge, and novel remediation technology. To learn about and register for the other sessions in this webinar series, please see the SRP website. To view this archive online or download the slides associated with this seminar, please visit http://www.clu-in.org/conf/tio/SRPPIR20_050523/