A podcast about computational biology, bioinformatics, and next generation sequencing.
https://bioinformatics.chat
episode 15: Optimal transport for single-cell expression data with Geoffrey Schiebinger
Geoffrey Schiebinger explains how reconstructing developmental trajectories from single-cell RNA-seq data can be reduced to the mathematical problem called optimal transport.
Links:
- Reconstruction of developmental landscapes by optimal-transport analysis of single-cell gene expression sheds light on cellular reprogramming.
- Talk by Geoffrey and Lénaïc Chizat
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