This webinar series explores challenges and opportunities for integrating datasets to solve complex environmental health problems. In the third session, speakers include data science experts who are developing tools through NIH-funded grants to establish infrastructure to coordinate data and develop sophisticated approaches to utilize big data to advance our understanding of human health and disease. Susan Teitelbaum, Ph.D. Associate Professor in the Department of Preventive Medicine at Icahn School of Medicine at Mount Sinai, Patricia Kovatch, Associate Dean for Scientific Computing and Associate Professor at the Icahn School of Medicine at Mount Sinai, and Deborah McGuinness, Ph.D., Computer Science Professor at Rensselaer Polytechnic Institute, will discuss their previous work related to knowledge integration and developing data infrastructure. They will also discuss their recent NIEHS Children's Health Exposure Analysis Resource (CHEAR) Data Repository, Analysis, and Science Center award, which will address methodology for combining data from a wide range of environmental health studies. Gregory Cooper, M.D., Ph.D., Professor of Biomedical Informatics at the University of Pittsburgh, will discuss the Center for Causal Discovery, an inaugural member of the NIH Big Data to Knowledge (BD2K) Consortium. Cooper leads the Center, which is developing and making available the algorithms, software, and system architecture needed by biomedical scientists seeking to discover causal relationships using large and diverse data sets. To view this archive online or download the slides associated with this seminar, please visit http://www.clu-in.org/conf/tio/IntegratingData3_110415/