David A. Katzka, MD, FACG, co-author of the American College of Gastroenterology's new Clinical Guideline on the Diagnosis and Management of Esophageal Eosinophilia and Eosinophilic Esophagitis (EoE), talks with AJG Co-editor Dr. Paul Moayyedi about the key components of the guidelines, including the epidemiology of the disease, the difficulty of diagnosis for EoE, the role of diet and pharmacological therapy for treatment of EoE, and the urgent need for more research into this disease.