Sieglinde Angelberger, MD, and David Berry, PhD, co-authors of new research on the efficacy of fecal microbiota transplantation (FMT) in patients with ulcerative colitis published in the October issue of AJG, talk with AJG co-Editor Dr. Paul Moayyedi about the highlights of their case series, including choice of stool donors, route and duration of administration, impact of FMT on these patients' gut microbiota, and what the disappointing response to FMT in these ulcerative colitis cases suggests for further research into this practice.