Die Hermann-Staudinger-Lecture Series ist eine im Jahr 2008 von der School of Soft Matter Research initiierte Vortragsreihe, zur der die naturwissenschaftlichen FRIAS Schools zwei- bis dreimal jährlich meist internationale Nobelpreisträger zu einem Vortrag nach Freiburg einladen. Die Vortragsreihe wurde nach dem Freiburger Nobelpreisträger Prof. Hermann Staudinger benannt, der von 1926-1951 an der Freiburger Universität lehrte. Staudinger's groundbreaking elucidation of the nature of the high-molecular weight compounds he termed Makromoleküle paved the way for the birth of the field of polymer chemistry. Staudinger himself saw the potential for this science long before it was fully realized. He was appointed a Professor at Albert-Ludwig University Freiburg in 1926 and founded the first polymer chemistry journal in 1940. In 1953 Staudinger received the Nobel Prize in Chemistry for his discoveries in the field of macromolecular chemistry.
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21st Hermann Staudinger Lecture with Nobel Laureate Randy Schekman (Howard Hughes Medical Institute, University of California, Berkely), 09.03.2016
Unconventional secretion of proteins and RNA from cultured human cells Large particles, such as lipoproteins, collagen and extracellular vesicles are secreted from animal cells in vivo and in cell culture. These particles represent a challenge for the normal secretory machinery. We have found that the rigid rod of procollagen can be accommodated in a giant transport vesicle dependent on the usual machinery involved in traffic from the endoplasmic reticulum. Extracellular vesicles are secreted by budding into an endosome or from the cell surface. Extracellular vesicles package a select set of micro RNAs that are sorted by an RNA binding protein and are dependent on a short nucleotide sequence that constitutes an RNA sorting signal.