How do scientists uncover phenomena and explain their connections? How do engineers design machines, methods and infrastructure? At omega tau, experts give detailed answers. Over the last ten years, we have produced over 350 episodes in which we dug deeper, until we ran out of questions. Join us on our journey through the world of science and engineering: the closer you look and listen, the more interesting things get.
https://omegataupodcast.net
292 – Gene Editing with CRISPR/Cas
CRISPR is a family of DNA sequences in bacteria and archaea that are a part of these organisms' cellular defense system. A recent discovery showed how this mechanism can be used to edit genes much more easily than legacy methods. In this episode I chat with Sam Sternberg about the naturally occuring CRISPR systems, how they work, and how CRISPR together with its associated enzymes can be used to cut, and subsequently, edit, DNA. We conclude the episode with an outlook on the potential use in medicine.