Each episode of AJP Audio brings you an in-depth look at one of the articles featured in that month’s issue of The American Journal of Psychiatry, the official journal of the American Psychiatric Association. Wide-ranging interviews with article authors cover the background, rationale, main findings, and future implications of the research. This podcast is subject to the Terms of Use at ww.psychiatry.org. The views and opinions expressed in this podcast are those of the individual speakers only and do not necessarily represent the views of the American Psychiatric Association, its officers, trustees, or members. The content of this podcast is provided for general informational purposes only and is not intended as, and shall not be understood or construed as, medical or any other type of professional advice nor does it represent any statement of the standard of care. We strongly recommend that any listener follow the advice of physicians directly involved in their care and contact their local emergency response number for any medical emergency. The information within this podcast is provided as-is and is not guaranteed to be correct, complete, or accurate.
https://ajp.psychiatryonline.org/audio
March 2022: Genetics and Brain Transcriptomics of Completed Suicide
Dr. Giovanna Punzi and Dr. Daniel Weinberger (Lieber Institute for Brain Development, Baltimore, Maryland) discuss findings from their new paper, “Genetics and Brain Transcriptomics of Completed Suicide,” which looks at differences in the brains of those who die by violent versus less violent means of suicide. Afterwards, Journal Editor-in-Chief Dr. Ned Kalin discusses what pulls the March issue of AJP together.
- Punzi and Weinberger interview [00:43]
- What made the two categories distinct? [02:28]
- Aggression as a factor [03:43]
- Differences in genetic factors [04:58]
- Potential heterogeneity of suicide [06:28]
- Counterintuitive conclusions [07:42]
- Clinical implications for those at risk for suicide [11:00]
- Next steps for research [11:43]
- Kalin interview [12:56]
- McMahon [13:58]
- Jacquemont et al. [14:22]
- Mancini et al. [15:53]
- Mahjani et al. [18:40]
- Leckman [21:22]
- Punzi et al. [21:48]
- Ecker et al. [25:38]
- Summary [28:45]
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