Pediatric Research Podcast

Pediapod is the pediatrics podcast from Pediatric Research, produced in association with Nature Publishing Group. Join us as we explore the etiologies of diseases of children and disorders of development, featuring interviews with top researchers and highlighted content from one of the premier journals in the field of pediatrics. Hosted on Acast. See acast.com/privacy for more information.

http://www.nature.com/pr/podcasts/index.html

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Sex-specific effects of prenatal opioid exposure


Neonatal opioid withdrawal syndrome (NOWS) represents a major public health problem in the US with a high socioeconomic burden. The pathophysiology of this condition is not yet fully understood. Data from animal models have shown that opioids modulate brain reward signalling via an inflammatory cascade, however no such data exist for opioid-exposed neonates.


In this episode of Pediapod we meet Early Career Investigator Elizabeth Yen, an assistant professor of pediatrics at Tufts University School of Medicine. She recently published a pilot study which looked at the effects of prenatal opioid exposure on gene expression and white matter injury. 


Read the full study here: Sex-specific inflammatory and white matter effects of prenatal opioid exposure: a pilot study | Pediatric Research (nature.com)


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 January 27, 2023  13m