This Week in Virology

TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.

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episode 992: Clinical update with Dr. Daniel Griffin


In his weekly clinical update, Dr. Griffin discusses clearance of longstanding, immune-deficiency-associated, vaccine-derived poliovirus infection following remdesivir therapy for chronic SARS-CoV-2 infection, SARS-CoV-2 exposure in New York City rats, clinical characteristics and outcomes of children with SARS-CoV-2 infection during the Delta and Omicron variant-dominant periods in Korea, exhaled breath aerosol shedding of SARS-CoV-2 variants, outpatient treatment of COVID-19 and the development of long COVID over 10 months, Nirmatrelvir and the risk of post-acute sequelae of COVID-19, assessment of the risk of venous thromboembolism in nonhospitalized patients with COVID-19, and the optimal duration of systemic corticosteroids in COVID-19 treatment.

Click arrow to play Download TWiV 992 (19 MB .mp3, 32 min)

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Links for this episode
  • Clearance of vaccine-derived poliovirus following remdesivir therapy for SARS-CoV-2 infection (Frontiers) 
  • SARS-CoV-2 exposure in Norway rats from New York City (mBio)
  • Clinical characteristics and outcomes of children with SARS-CoV-2 Infection in Korea (JKMS)
  • Exhaled breath aerosol shedding of SARS-CoV-2 variants (CID)
  • Outpatient treatment of COVID-19 and the development of Long COVID (The Lancet) 
  • Nirmatrelvir and the risk of post-acute sequelae of COVID-19 (medRxiv)
  • Risk of venous thromboembolism in nonhospitalized patients with COVID-19 (JAMA)
  • Optimal duration of systemic corticosteroids in COVID-19 treatment (OFID)
  • Contribute to our ASTMH fundraiser at PWB
  • Dr. Griffin’s treatment guide (pdf)
  • Letters read on TWiV 992
  • Don’t crush Paxlovid (pdf)
  • Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv


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 March 18, 2023  31m