episode 1057: CMV-based HIV vaccine with Klaus Früh
Klaus Früh visits the Incubator to discuss his career and his work on cytomegalovirus-vectored vaccines which are unique in their ability to persistently maintain an immune shield of effector memory T cells, including highly unconventional MHC-II and MHC-E restricted CD8+ T cells.
Host: Vincent Racaniello, Rich Condit, and Brianne Barker
Guest: Klaus Früh
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Links for this episode- MicrobeTV Discord Server
- MicrobeTV store at Cafepress
- Spike shirts at vaccinated.us (promo code Microbetv)
- Research assistant position in Rosenfeld Lab CBER/FDA (pdf)
- HCMV-based attenuated vaccine platform (Sci Rep)
- HLA-E-restricted, Gag-specific CD8+ T cells suppress HIV-1 infection (Sci Immunol)
- RhCMV/SIV vaccine shows long-term efficacy against SIV challenge (Sci Transl Med)
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
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