episode 1092: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing new vaccine guidelines released by the advisory committee on immunization practices, and reviews the CDC guidelines for quarantine/ isolation following SARS-CoV-2 infection, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, the role of IFN-g in long COVID, if the brain-blood-barrier is compromised in long COVID, meaning of persistent community SARS-CoV-2 RNA findings, and the effects of hyperbaric oxygen on post COVID neurocognition.
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Links for this episode- Respiratory disease surveillance (CDC)
- RSV surveillance (CDC)
- RSV national trend (CDC)
- RSV vaccination stats (CIDRAP)
- Influenza/flu surveillance (CDC)
- Influenza/flu map (CDC)
- COVID-19 hospital admissions (CDC)
- COVID-19 national trend (CDC)
- COVID-19 wastewater testing (biobot)
- Variant tracker (CDC)
- Variant hospital admissions (CDC)
- ACIP COVID vaccination for seniors recommendations (CIDRAP)
- Additional vaccine doses for older adults (CDC)
- Evidence based advice from the ACIP (CDC)
- State mandates did NOT influence primary vaccination rates only boosters (PNAS)
- No nOPV2? (CDC)
- CDC Quarantine guidelines (CDC)
- To rebound or to not rebound (MMWR)
- Know your COVID-19 tools (ESMED)
- How to pay for Paxlovid (PAXCESS)
- Molnupiravir safety and efficacy (JMV)
- Molunpiravir plus antibody therapy for at-risk outpatients (Nat Comm)
- Convalescent plasma recommendation for immunocompromised (IDSociety)
- Steroids, dexamethasone at the right time (OFID)
- Anticoagulation guidelines (hematology.org)
- Spontaneous release of IFN-g in Long COVID (Science Advances)
- Blood-brain-barrier compromise in long COVID associated cognitive impairment (Nat Neuroscience)
- Persistent community SARS-CoV-2 RNA (Nature)
- Hyberbaric oxygen therapy improves post COVID neurocognition (Scientific Reports)
- Medical study questionnaire, the SHORT form (Brandeis)
- Long term effects of hyperbaric oxygen post COVID (Scientific Reports)
- Contribute to our ASTMH fundraiser at PWB
- Letters read on TWiV 1092
- Dr. Griffin’s COVID treatment summary (pdf)
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv