This Week in Virology

TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.

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episode 1104: Clinical update with Dr. Daniel Griffin


In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles before addressing results of Pfizer’s phase 3 RSV vaccine clinical trial for adults under 60, RSV, influenza and SARS-CoV-2 circulation, differences between rural and urban communities dealing with SARS-CoV-2 infections, the latest statistics on influenza and COVID-19 circulation, restates the guidelines for spring administration of COVID vaccines boosters, discusses the emergency use application of a pre-exposure prophylactic. revised guidelines for how to treat respiratory viral infection guidelines by the CDC, continues to dispel the myth of viral rebound, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, how long COVID affects the brain and associates with an increase in allergic incidents as well as if post SARS-CoV-2 infected patients are unable to exercise or have functional limitations. For more information about this body of work, listen to TWiV 1088.

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Links for this episode
  • Measles tracking (CDC)
  • Measles just this year (MMWR)
  • ABRYSVO phase 3 results (Pfizer)
  • RSV surveillance (CDC)
  • Influenza/flu surveillance  (CDC)
  • Provisional deaths due to COVID-19 (CDC)
  • COVID-19 national trend (CDC)
  • COVID-19 wastewater testing (biobot)
  • Variant tracker (CDC)
  • Rural-urban differences in COVID-19 mortality and hospitalizations (OFID)
  • Spring COVID-19 booster recommendations (CIDRAP)
  • Older adult spring booster available (CDC)
  • Advisory committee for immunization practices spring 2024 COVID-19 boosters (CDC)
  • EUA for pemgarda (FDA)
  • CDC Quarantine guidelines (CDC)
  • NIH COVID-19 treatment guidelines (NIH)
  • Nirmatrelvir for vaccinated or unvaccinated COVID-19 patients (NEJM)
  • Assessment for clinical usefulness (NEJM)
  • Molnupiravir safety and efficacy (JMV)
  • Convalescent plasma recommendation for immunocompromised (IDSociety)
  • Updated respiratory virus guidances (CDC)
  • What do when your heathcare provider is infected with SARS-CoV-2 (CDC)
  • Managing healthcare staffing shortages (CDC)
  • Steroids,dexamethasone at the right time (OFID)
  • Anticoagulation guidelines (hematology.org)
  • Long COVID evidence based review TWiV shout out (TWiV 1088)
  • Brian and cognitive changes in long COVID patients (BRAIN)
  • Allergic disease incidents after COVID-19 (Nat Comm)
  • Can post COVID patients exercise or do they have functional limitations (JAMA Network Open)
  • Contribute to our ASTMH fundraiser at PWB 37:06
  • Letters read on TWiV 1102 37:56
  • Dr. Griffin’s COVID treatment summary (pdf)
  • Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv


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