episode 519: Fishing for viruses in senile
The TWiVomers review a potential role for herpes simplex virus type 1 as a cause of Alzheimer's Disease, including the finding that amyloid-beta acts as an antiviral by enveloping virus particles.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker
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Links for this episode- Virology Comics on sale (Amazon)
- Clinical Trial: antiviral for AD
- HHV6 and HHV7 transcripts in AD brain (TWiV 505)
- HSV1 in AD (Front Ag Neuro)
- Taiwan cohort study on antivirals and AD (Neurother)
- HSV1 antibodies in CSF (J Med Virol)
- HSV1 induces amyloid-beta fibrillization (Neuron)
- Image credit
- Letters read on TWiV 519
- Timestamps by Jolene. Thanks!
Brianne - Pandemic (board game)
Alan- The Shortwave Radio Audio Archive (siteand blog)
Rich- James Cook's First Pacific Voyage, 1768-1771 (interactive map)
Dickson- The Scientist on Instagram
Vincent - State of the World’s Fungi
David- Bruno LaTour
Intro music is by Ronald Jenkees.
Send your virology questions and comments to twiv@microbe.tv